Amino acid racemization dating
Racemization occurs when one pure form of an enantiomer is converted into equal proportion of both enantiomers, forming a racemate.When there are both equal numbers of dextrorotating and levorotating molecules, the net optical rotation of a racemate is zero.Racemization can be achieved by simply mixing equal quantities of two pure enantiomers.
The two forms, which are non-superposable when rotated in 3-dimensional space, are said to be enantiomers. (1977) Amino acid studies of the Del Mar, California midden site: apparent rate constants, ground temperature models, and chronological implications. Belknap (1978) Alternative kinetic models for the interpretation of amino acid enantiomeric ratios in Pleistocene mollusks: examples from California, Washington, and Florida. If only one enantiomer is administered to a human subject, both forms may be found later in the blood serum.Another commonly used drug is ibuprofen which is only anti-inflammatory as one enantiomer while the other is biologically inert.